Fig. 5: Effect of 740Y-P on the PI3K/AKT/ΔFosB/AQP4 pathway in primary astrocytes. | Cell Death & Disease

Fig. 5: Effect of 740Y-P on the PI3K/AKT/ΔFosB/AQP4 pathway in primary astrocytes.

From: Dexmedetomidine improves the circulatory dysfunction of the glymphatic system induced by sevoflurane through the PI3K/AKT/ΔFosB/AQP4 pathway in young mice

Fig. 5

A Cell viability of primary astrocytes. B–F Western blot and quantitative analysis of p-PI3K, PI3K, p-AKT, AKT, ΔFosB, and AQP4 in primary astrocytes(n = 4). G, H Immunofluorescence and quantitative analysis of ΔFosB in primary astrocytes(n = 3, scale bar = 50 μm). Data are expressed as the mean ± SD, *p < 0.05, ***p < 0.001. One-way ANOVA and Tukey’s post-hoc test.

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