Fig. 6: ONECUT2 correlation with GC patient prognoses. | Cell Death & Disease

Fig. 6: ONECUT2 correlation with GC patient prognoses.

From: Increased ONECUT2 induced by Helicobacter pylori promotes gastric cancer cell stemness via an AKT-related pathway

Fig. 6

A Representative image of ONECUT2 immunohistochemistry (IHC) staining in human GC tissue microarrays at our center. B Standard scoring for ONECUT2 IHC staining intensity. C Distribution of ONECUT2 expression levels in GC and adjacent non-tumor tissue as assessed by IHC. D Association between high and low ONECUT2 levels and overall survival of 135 GC patients from our center (P = 0.008). E Comparison of overall survival rates of GC patients grouped by high or low expression of ONECUT2 mRNA, using public data (P = 0.004). F A K-M survival curve shows that patients with HP infection have a lower overall survival rate (HR = 2.087, P = 0.010) compared with those without HP infection. G Multivariable Cox regression analysis for overall survival in tissue microarray cohort. Scale: 100 μm.

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