Fig. 2: UBTD1 promotes the proliferation and migration of CRC cells. | Cell Death & Disease

Fig. 2: UBTD1 promotes the proliferation and migration of CRC cells.

From: The ubiquitin-like protein UBTD1 promotes colorectal cancer progression by stabilizing c-Myc to upregulate glycolysis

Fig. 2

A The UBTD1 mRNA and protein were detected using qRT-PCR and WB to validate the overexpression of UBTD1 in HCT116 and P53R cell lines. B The UBTD1 mRNA and protein were detected using RT-PCR and WB to validate the knockdown of UBTD1 in HCT116 and P53R cell lines. C CCK-8 was used to assess the proliferation after UBTD1 overexpression in HCT116 and P53R cell lines. D CCK-8 was used to assess the proliferation after UBTD1 knockdown in HCT116 and P53R cell lines. E Colony formation assay was used to assess the proliferation after UBTD1 overexpression in HCT116 and P53R cell lines. F Colony formation assay was used to assess the proliferation after UBTD1 knockdown in HCT116 and P53R cell lines. G Transwell chamber assay was used to assess migration after UBTD1 overexpression in HCT116 and P53R cell lines; H Transwell chamber assay was used to assess migration after UBTD1 knockdown in HCT116 and P53R cell lines. **P < 0.01 or *** P < 0.001 indicates a significant difference between the indicated groups.

Back to article page