Fig. 2: NOP2 promotes migration and invasion of lung cancer cells.

A, B RT-qPCR was performed to verify the overexpression and knockdown efficiency of NOP2. C, D Western blot was performed to verify the overexpression and knockdown efficiency of NOP2. E–H The migration ability of lung cancer cells was determined by wound-healing assays. Scale bar = 100μm. I–L The invasion ability of lung cancer cells was shown by transwell assays. Scale bar = 100μm. Statistical methods: independent samples t-test (A, E, F, I, J), one-way ANOVA (B, G, H, K, L). Data are shown as the mean ± SEM of at least 3 independent experiments. *p < 0.05, **p < 0.01, ***p < 0.001.