Fig. 1: AQP3 expression in LUAD correlates with poorer outcome.

A Relative mRNA expression levels of AQP3 in LUAD tissues and normal lung tissues determined by RT-qPCR. B, C Western blot analysis of AQP3 protein expression in stage I LUAD tissues and corresponding adjacent normal tissues (n = 12). D, E Representative images of AQP3 protein expression in stage I LUAD tissues and adjacent tissues detected by IHC, and corresponding H-score quantification using ImageJ IHC Profiler. F Correlation of AQP3 expression with clinicopathological characteristics of LUAD patients. G Kaplan-Meier survival analysis of progression-free survival (PFS) and overall survival (OS) in LUAD patients stratified by AQP3 protein expression. **P < 0.01, ***P < 0.001.