Fig. 3: Detailed classification of macrophage subsets in LUAD. | Cell Death & Disease

Fig. 3: Detailed classification of macrophage subsets in LUAD.

From: PPAR-γ/NF-kB/AQP3 axis in M2 macrophage orchestrates lung adenocarcinoma progression by upregulating IL-6

Fig. 3

A UMAP plot displaying the five TAM subclusters identified in adjacent lung and LUAD samples. B Heatmap showing the top 15 highly expressed genes in each of the distinct macrophage subpopulations. C Violin plots displaying the expression levels of AQP3, CD206, CD163, IL-1B, TLR2, and MKI67 in different macrophage subtypes. D UMAP plot displaying the expression of AQP3 in each of the TAM subclusters. E Immunofluorescent staining showing the expression and co-localization of AQP3 and CD163 in adjacent lung and LUAD tissues.

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