Fig. 4: AQP3 was highly expressed in M2 macrophages and regulated the polarization of M2 macrophages. | Cell Death & Disease

Fig. 4: AQP3 was highly expressed in M2 macrophages and regulated the polarization of M2 macrophages.

From: PPAR-γ/NF-kB/AQP3 axis in M2 macrophage orchestrates lung adenocarcinoma progression by upregulating IL-6

Fig. 4

A, B RT-qPCR analysis of AQP3 and macrophage marker gene expression in different types of macrophages derived from THP-1 or RAW264.7 cells. C, D Western blot analysis of AQP3 and CD163 protein expression in THP-1 cells and different types of macrophages. E, F Flow cytometry analysis of CD163 expression in human or mouse-derived macrophages. G, H Immunofluorescence staining of AQP3 and CD163 expression in THP-1 or RAW264.7-derived macrophages after overexpression or knockdown of AQP3. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001.

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