Fig. 1: DDR and senescence markers are activated in adipose tissue of obese individuals.
From: The dual nature of DNA damage response in obesity and bariatric surgery-induced weight loss
Box plots resulting from comparison of RPPA profiles of biopsies of subcutaneous adipose tissue (SAT) and visceral adipose tissue (VAT) of severely obese patients (OB-SAT and OB-VAT) and normal-weight (NW) controls (a–h). The plots represent the distribution of RPPA intensity values (median ± SD). Statistical comparisons were performed with Wilcoxon rank sum test as non-parametric test and t-test as parametric test for not-paired samples (black brackets). Paired samples were compared using Wilcoxon signed-rank test as non-parametric test and t-test as parametric test (blue brackets). Statistical significance is coded with an asterisk according to the level of significance (*p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001).
