Fig. 4: Metabolic redesign occurs in PBMC after bariatric surgery.
From: The dual nature of DNA damage response in obesity and bariatric surgery-induced weight loss
Box plots resulting from the comparison of RPPA profiles of peripheral blood mononuclear cells (PBMCs) of severely obese patients before (T0) and six (T6), and 12 (T12) months after bariatric surgery and their normal-weight (NW) controls. a–e The plots represent the distribution of RPPA intensity values (mean ± SD), and statistical comparisons were performed using the Wilcoxon rank sum test for the comparison between OB and NW subjects. For the comparison at the different times, we used two tests for paired samples: Wilcoxon signed-rank test as non-parametric test and t-test as parametric test. Statistical significance is coded with an asterisk according to the level of significance (*p ≤ 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001).
