Fig. 5: Loss of Shp2 in rods alters cellular metabolism. | Cell Death & Disease

Fig. 5: Loss of Shp2 in rods alters cellular metabolism.

From: Age-related retinal degeneration resulting from the deletion of Shp2 tyrosine phosphatase in photoreceptor neurons

Fig. 5

Unsupervised hierarchical clustering glycolytic transcripts between rod fractions of rodShp2 WT and KO mice (A). Unsupervised hierarchical clustering pentose phosphate shunt (PPS) transcripts between rod fractions of rodShp2 WT and KO mice (B). Unsupervised hierarchical clustering TCA Cycle transcripts between rod fractions of rodShp2 WT and KO mice (C). Unsupervised hierarchical clustering of mitochondrial transcripts between rod fractions of rodShp2 WT and KO mice (D). Unsupervised hierarchical clustering of fatty acid oxidation transcripts between rod fractions of rodShp2 WT and KO mice (E). Unsupervised hierarchical clustering of antioxidant transcripts between rod fractions of rodShp2 WT and KO mice (F).

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