Fig. 1: Single cell transcriptome map and major cell types in ESCC tumor microenvironment.

A Single cell sequencing process. B Cell types and UMAP of all samples. C Heat maps of typical marker gene expression by cell types. D The proportional contribution of tissue samples to each cell type. E Proportion of each cell type in the four groups. F Proportion of immune cell components in four groups. The interactions between cell types shown in the form of (G) heat map and (H) shell map. P < 0.05. *P < 0.05; **P < 0.01; ***P < 0.001.