Fig. 3: The developmental trajectory of B cells in MM. | Cell Death & Disease

Fig. 3: The developmental trajectory of B cells in MM.

From: Single-cell sequencing analysis of multiple myeloma heterogeneity and identification of new theranostic targets

Fig. 3

A Pseudotemporal analysis scores of expression profiles. B Pseudotemporal analysis of divergence trajectories between HDs and MM patients. C Pseudotemporal analysis of the divergent trajectories of each subgroup. D Heatmap showing gene enrichment on the two branches after the bifurcation point. E Results of Gene Ontology Biological Process (GO-BP) analysis of differences in Cluster 2. F Expression of the mitochondria-related genes NDUSF2, NDUSF5, and NDUDF7; the cycle-related gene CDKN2A; the autophagy-related gene HMGB1; and the lipid metabolism-related gene FABP5 according to the differentiation trajectory of the expression profile.

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