Fig. 6: NUF2 regulate the transcription of magnesium ion transporters by H3K4me3. | Cell Death & Disease

Fig. 6: NUF2 regulate the transcription of magnesium ion transporters by H3K4me3.

From: Maintenance of magnesium homeostasis by NUF2 promotes protein synthesis and anaplastic thyroid cancer progression

Fig. 6

A Relative luciferase activity in 293T cells treated with pcDNA3.1 empty vector and NUF2 plasmids. B Max-Z score of H3K4me3 and H3K27ac in the thyroid glands of four patients. C Double immunofluorescence for NUF2 and H3K4me3 in 8505 C and Nthy-ori 3-1 cells. D Coimmunoprecipitation (CoIP) assay of NUF2, H3K4me3 and H3K27ac. E–G The abundance of H3K4me3 at the MAGT1, NIPA1 and NIPAL1 promoters in ATC cell lines was analyzed by chromatin immunoprecipitation. Data are presented as the mean ± SD. *P < 0.05, **P < 0.01, ***P < 0.001.

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