Fig. 5: Gpx4 OE and RTAs additively augment cold resistance of mouse primary hepatocytes.
From: Identification of genes supporting cold resistance of mammalian cells: lessons from a hibernator
a Schematic illustration of experimental time course. b Overexpression of Gpx4 protein was confirmed by immunoblot of hepatocytes infected with the AAV vectors expressing GFP or maGpx4. c The proportion of dead cells in hepatocytes infected with the AAV vectors expressing GFP or maGpx4 after 24 h cold culture with DMSO or 200 µM BH2 and/or 10 µM αTocopherol (αT) (one-way ANOVA with the Dunnett’s multiple comparison test compared to GFP-DMSO, *p < 0.05, **p < 0.01, ***p < 0.001).
