Fig. 12: The proposed signaling carton of the present study.
From: Identification of Gαi3 as a promising molecular oncotarget of pancreatic cancer

The current study emphasizes the complex role of Gαi3 in promoting the growth of pancreatic cancer cells by regulating the Akt-mTOR and PKA-Hippo-YAP signaling pathways. TCF7L2 is a crucial transcription factor for Gαi3, driving its upregulation in pancreatic cancer.