Fig. 4: The impact of Nme8 deletion on sperms under CP stimulation was tested. | Cell Death & Disease

Fig. 4: The impact of Nme8 deletion on sperms under CP stimulation was tested.

From: Nme8 is essential for protection against chemotherapy drug cisplatin-induced male reproductive toxicity in mice

Fig. 4

A H&E staining was performed on a smear of sperms from the epididymis cauda. Scale bar = 20 μm. The black arrows point to normal sperm, and the red, green, and yellow arrows point to abnormal head, coiled tail, and decapitated sperm, respectively. B–D The percent of abnormal sperms was calculated. E The concentration of sperms in different groups of mice under the same treatment condition. F–H The CASA analysis was used to test sperm motility, including progressive motility, nonprogressive motility, and immobilized sperms. I, J The straight-line and curvilinear velocity of sperms were tested. *P < 0 .05, ***P < 0.001, NS indicates non-significant, n = 4 biologically independent mice in each group.

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