Fig. 3: The impact of USP11 on cellular apoptosis was mediated by regulating the Nrf2/ARE signaling pathway. | Cell Death & Disease

Fig. 3: The impact of USP11 on cellular apoptosis was mediated by regulating the Nrf2/ARE signaling pathway.

From: The USP11/Nrf2 positive feedback loop promotes colorectal cancer progression by inhibiting mitochondrial apoptosis

Fig. 3

A KEGG pathway enrichment analysis. HCT116/DLD1 cells were transfected with siRNAs to knock down USP11 protein. B, C Flow cytometric detection of total ROS and MitoSOX levels. (n = 3). D Analysis of GSH levels. (n = 3). E, F qPCR and WB analysis of the expression of Nrf2/ARE, Nrf2 protein level decreased, but its mRNA level was not affected. (n = 3).

Back to article page