Fig. 4: MALAT1 interacts with the splicing factor SFPQ.
From: LncRNA MALAT1 promotes Erastin-induced ferroptosis in the HBV-infected diffuse large B-cell lymphoma

A, B GO (A) and KEGG enrichment (B) analysis of the MALAT1 interaction proteins. C The CatRAPID signature module predicted the binding capacity of the SFPQ protein and MALAT1. D, E The CatRAPID fragments module predicted the interaction spectrum (D) and matrix (E) between the SFPQ protein and MALAT1. F The analysis of the interaction site between MALAT1 and SFPQ. G Immunofluorescence staining of the SFPQ (green) in SUDHL-4 cells. Nuclei were stained with Hoechst33342 (blue). Scale bar, 20 μm. H Schematic diagram of the full-length MALAT1 and MALAT1 deletion mutant (Δ301–362 nt). I RIP assay detected the interaction between SFPQ and wild-type MALAT1 or MALAT1 deletion mutant in SUDHL-4 cells. The results were determined in triplicate, and the error bars represented the mean ± SD. ns P > 0.05 and *P < 0.05.