Fig. 3: Mist1KO mice are more susceptible to CCl4-induced stress. | Cell Death & Disease

Fig. 3: Mist1KO mice are more susceptible to CCl4-induced stress.

From: MIST1 regulates endoplasmic reticulum stress-induced hepatic apoptosis as a candidate marker of fatty liver disease progression

Fig. 3

A Experimental scheme. B, C Levels of blood serum transaminases; n ≥ 3 per group. D Triglyceride content in the caudate lobe; n = 9 per group. E, G, I, K, and M H&E, Oil-red-O, Sirius red, F4/80 immunohistochemistry, and TUNEL immunofluorescence in Mist1KO mice and wild-type (WT) littermates treated with CCl4. F Ballooning degeneration, H lipid droplet accumulation, J fibrotic area, L macrophage recruitment, and N apoptotic cell counts in tissue sections; n = 9 per group, (CV central vein, PV portal vein). All data are presented as mean ± SEM.

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