Fig. 5: Emerging connectivity and crosstalk between lipid peroxidation and regulated cell death.
From: Emerging mechanisms of lipid peroxidation in regulated cell death and its physiological implications

Currently, a more complex network between the lipid peroxidation and different cell death pathways has been established over the years. Uncontrolled lipid peroxidation damages cellular membrane and lead to cell death. Then, the release of DAMPs from cell death might further exacerbate lipid peroxidation and trigger other cell death patterns.