Fig. 3: LINC01016 is associated with BC progression. | Cell Death & Disease

Fig. 3: LINC01016 is associated with BC progression.

From: SP-1-activated LINC01016 overexpression promotes gastric cancer invasion and metastasis through inhibiting EIF4A3-mediated MMP9 mRNA decay

Fig. 3

A, B Transwell assays show that LINC01016 overexpression promoted cell migration and invasion, while konckdown this gene inhibited cell migration and invasion. C–E Colony formation EDU and MTS assays demonstrate that either overexpression or knockdown LINC01016 had no substantial influence on GC cell proliferation. F–G Flow cytometry assays show that LINC01016 did not affect on cell apoptosis or cell cycle distribution. H Transwell assays show that overexpression of ETS-1 enhances the ability of cell migration and invasion. Scale bar: 100 μm. Data are shown as mean ± SEM of three independent experiments, *P < 0.05, **P < 0.01,***P < 0.001, ns. not significant.

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