Table 2 Univariate and multivariate Cox proportional hazards regression analysis of overall survival and disease-free survival after surgery.
variable | univariate analysis | multivariate analysis | ||||
|---|---|---|---|---|---|---|
P value | HR | 95% CI | P value | HR | 95% CI | |
overall survival | ||||||
Age (< 60 years vs. ≥ 60 years) | 0.254 | 0.687 | 0.360–1.310 |  |  |  |
Gender (Female vs. Male) | 0.899 | 0.954 | 0.463–1.966 |  |  |  |
Differentiation (Moderate vs.Poor) | 0.021 | 0.461 | 0.240–0.888 | 0.658 | 1.181 | 0.565– 2.471 |
Tumor size(> 4 cm vs. ≤4 cm) | 0.14 | 1.626 | 0.853–3.098 |  |  |  |
T stage (T1/2 vs. T3/4) | 0.061 | 0.516 | 0.258–1.031 |  |  |  |
N stage (N0 vs. N1/2/3) | <0.0001 | 0.231 | 0.119–0.447 | 0.002 | 0.200 | 0.072–0.545 |
Expression of LINC01016 (Low vs. High) | 0.001 | 0.336 | 0.173–0.653 | 0.045 | 0.414 | 0.175–0.980 |
Disease-free survival | ||||||
Age (< 60 years vs. ≥ 60 years) | 0.065 | 0.578 | 0.323–1.035 |  |  |  |
Gender (Female vs. Male) | 0.337 | 0.733 | 0.389–1.382 |  |  |  |
Differentiation (Moderate vs.Poor) | 0.002 | 0.389 | 0.213–0.709 | 0.969 | 0.987 | 0.510–1.912 |
Tumor size(> 4 cm vs. ≤4 cm) | 0.017 | 2.02 | 1.132–3.604 | 0.419 | 0.764 | 0.398–1.468 |
T stage (T1/2 vs. T3/4) | 0.004 | 0.406 | 0.220–0.750 | 0.365 | 0.663 | 0.273–1.613 |
N stage (N0 vs. N1/2/3) | <0.0001* | 0.141 | 0.077–0.258 | 0.000 | 0.100 | 0.036–0.281 |
Expression of LINC01016 (Low vs. High) | 0.004 | 0.417 | 0.231–0.752 | 0.422 | 0.738 | 0.351–1.550 |
