Fig. 8: G3BP1 inhibition mproves cardiac function of myeloid-specific SHEP1 deficiency mice under MIRI.

A LysM Cre+ Shep1fl/fl mice and their Shep1fl/fl littermates were intraperitoneally infused with EGCG or PBS as control right after IR. Echocardiography was conducted 3 days later, and representative images are displayed with quantification of percentage ejection fraction (% EF) and percentage fractional shortening (% FS) (n = 6). All data are presented as mean ± SEM.