Fig. 4
From: Mitophagy in ischemic heart disease: molecular mechanisms and clinical management

Summary of the role of mitophagy in promoting the progression of ischemic heart disease: 1. Mitophagy promotes myocardial cell hypertrophy and fibrosis. 2. Mitophagy promotes inflammation. 3. Mitophagy promotes oxidative stress progression. 4. Mitophagy promotes cell death.