Fig. 7: RIPK1 antagonizes CD95L-induced DISC recruitment of the TRADD-TRAF2 dyad.
From: TRAF2 and RIPK1 redundantly mediate classical NFκB signaling by TNFR1 and CD95-type death receptors
Ligand-induced TNFR1- (A) and CD95-associated (B) signaling complexes were immunoprecipitated from the indicated HCT116-PIK3CAmut cell line variants via their respective Fc-linked ligands and co-precipitated proteins were analyzed by western blotting.
