Fig. 6: KLF5 is correlated with ZEB1 and HMOX1 in PDAC tissues. | Cell Death & Disease

Fig. 6: KLF5 is correlated with ZEB1 and HMOX1 in PDAC tissues.

From: Inhibition of KLF5 promotes ferroptosis via the ZEB1/HMOX1 axis to enhance sensitivity to oxaliplatin in cancer cells

Fig. 6

A Immunofluorescence of KLF5, ZEB1, and HMOX1 in tissues of patients with PDAC. B IHC staining of KLF5, ZEB1, and HMOX1 in tissues of patients with PDAC. C, D Statistical analysis of the correlation between expression of KLF5 and ZEB1, or KLF5 and HMOX1 (P was obtained using Pearson’s χ2 test). E The standard to evaluate IHC staining is shown in Fig. S4B. The correlation between the expression of ZEB1 and HMOX1 was analyzed (n = 82, Spearman r = 0.6471, P < 0.001). F ZEB1 was positively correlated with HMOX1 in the GEPIA dataset.

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