Fig. 1: piR-26441 was notably downregulated in OC. | Cell Death & Disease

Fig. 1: piR-26441 was notably downregulated in OC.

From: piR-26441 inhibits mitochondrial oxidative phosphorylation and tumorigenesis in ovarian cancer through m6A modification by interacting with YTHDC1

Fig. 1

a Volcano plot showing the differential expression of piRNAs between OC and normal ovarian tissue. b Heatmap showing down-regulated differential expression of piRNAs. c The expression levels of piR-26441 in OC tissue samples (n = 80) were lower than that in normal ovarian tissue samples (n = 18). d piR-26441 expression levels in FIGO stage III–IV diseases were lower than that in FIGO stage I-II diseases. e piR-26441 genomic location. f Expression levels of piR-26441 in OC cell lines. g Transfection efficiency of piR-26441 mimic and sh-piR-26441 in CAOV3 and OVCAR3. All independent experiment repeated three times. Values are presented as the mean ± SD. *p ≤ 0.05; **p ≤ 0.01; ***p ≤ 0.001.

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