Fig. 1: Sarcoglycan subunits are present in the NMJ.
From: Sarcoglycans are enriched at the neuromuscular junction in a nerve-dependent manner
A Dotplot map of clustered nuclei from snRNA-seq of Petrany et al. [46]. Subsynaptic nuclei represented inside a circle; pink dots. B Representation of sarcoglycans average expression level on the different analyzed clusters. C Magnification of dotplot map of sarcoglycans relative expression level in NMJ nuclei. D On the left, immunofluorescent representative images of Tibialis Anterior transversal sections from WT female at 1 month. Stain of sarcoglycans (red), AChR (green) and dapi (blue). Scale bar 100 μm. On the right, quantification of sarcoglycan signal in identical area size corresponding to sarcolemma section or NMJ section of the immunofluorescence images. n = 3. Analysis was made using t-test, *p < 0.05; **p < 0.01; ***p < 0.001.
