Fig. 2: The analysis of CD4+ T cell subsets of ACM patients revealed blood effector/memory CD4+ T regulatory cell increase and effector-memory CD8+ cell decrease. | Cell Death & Disease

Fig. 2: The analysis of CD4+ T cell subsets of ACM patients revealed blood effector/memory CD4+ T regulatory cell increase and effector-memory CD8+ cell decrease.

From: Analysis of effector/memory regulatory T cells from arrhythmogenic cardiomyopathy patients identified IL-32 as a novel player in ACM pathogenesis

Fig. 2

a, b Percentages of naive, CM, EM, and EMRA subsets in CD4+ T cells (a) or in CD8+ T cells (b) from controls (n = 21) and ACM patients (n = 18) as histograms. c Percentages of memory CD45RO+ CD4+ T helper subsets Th1-like, Th2-like, Th17-like and Th1*-like from ACM patients and age-matched controls (HC; n = 17 pairs). d, e Percentages (n = 18 per group) of mTreg and naive (nTreg) in CD4+ T cells (d) and geometric mean fluorescence intensity (n = 9 per group) of FOXP3 (e). f Analysis of mTreg and nTreg CD4+ T regulatory cell subsets of HC and ACM patients by flow cytometry based on CD45RO expression. Data are shown as mean ± SEM. **p < 0.01, *p < 0.05 and ns not significant using unpaired T-test (a, b) or Wilcoxon matched-pairs signed rank test (c–e).

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