Fig. 4: Differential expression analysis of Treg of ACM patients vs. HC revealed dysregulation of specific pathways and higher expression of IL-32. | Cell Death & Disease

Fig. 4: Differential expression analysis of Treg of ACM patients vs. HC revealed dysregulation of specific pathways and higher expression of IL-32.

From: Analysis of effector/memory regulatory T cells from arrhythmogenic cardiomyopathy patients identified IL-32 as a novel player in ACM pathogenesis

Fig. 4

a, c Pathway analysis of differentially expressed genes between HC and ACM mTreg (a) and for each cluster (c), according to NCI-Nature Pathway Database. b Heatmap showing log-fold change expression of genes in each of the 6 clusters with significant ANOVA test (p > 0.01) between ACM and control identifying IL-32.

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