Fig. 4: CrT−/y mitochondria present morphological abnormality. | Cell Death & Disease

Fig. 4: CrT−/y mitochondria present morphological abnormality.

From: Creatine transporter (SLC6A8) knockout mice exhibit reduced muscle performance, disrupted mitochondrial Ca2+ homeostasis, and severe muscle atrophy

Fig. 4

Representative electron microscopy pictures of EDL muscle fibers in control (A) and CrT−/y mice (B) and (C). Scale bars: 1 μm (insets: 0.1 μm). D Quantitative EM analysis. Data are presented as mean ± SEM. Sample size: 15 fibers from 1 WT mice, 30 fibers from 2 CK-KO mice; 5 micrographs/fiber. For data analysis, parametric Student t-test (two-tailed, unpaired) was used. *p < 0.05.

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