Fig. 2: TRIM21 inhibits the proliferation of CRC cells in vitro. | Cell Death & Disease

Fig. 2: TRIM21 inhibits the proliferation of CRC cells in vitro.

From: TRIM21-mediated PRMT1 degradation attenuates colorectal cancer malignant progression

Fig. 2

A–D CCK-8 and colony formation assays were used to assess the effect of TRIM21 knockdown (A, B) or overexpression (C, D) on cell proliferation in HCT-116 and LoVo cell lines. E, F The impact of TRIM21 knockdown (E) or overexpression (F) on the major cyclins were detected by western blot analysis. Data are represented as mean ± SD of three independent experiments, and ***p < 0.001 (Student’s t-test).

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