Fig. 7: HK2 downregulation reverses STAT3-mediated PC progression. | Cell Death & Disease

Fig. 7: HK2 downregulation reverses STAT3-mediated PC progression.

From: CDCA7 enhances STAT3 transcriptional activity to regulate aerobic glycolysis and promote pancreatic cancer progression and gemcitabine resistance

Fig. 7

A–C CCK-8, plate cloning, and EDU assays were performed to examine cell proliferation in each group. D–G Migratory and invasive abilities of cells in each group were determined using scratch and Transwell assays. H–J Lactate (H), glucose (I), and ATP levels (J) in each group. K Aerobic glycolysis was assessed in each group, based on ECAR. L CCK-8 assay was performed to examine the resistance of PC cells to gemcitabine in each group. *P < 0.05, **P < 0.01, ***P < 0.001.

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