Fig. 3: Mitochondrial MTCH2 is upregulated in both CRPC tissue and cells. | Cell Death & Disease

Fig. 3: Mitochondrial MTCH2 is upregulated in both CRPC tissue and cells.

From: Identification of mitochondrial carrier homolog 2 as an important therapeutic target of castration-resistant prostate cancer

Fig. 3

Expression levels of MTCH2 mRNA (A) and protein (B, C) in the CRPC tissue (“T”, derived from 15 different CRPC patients) or tumor-surrounding normal prostate tissue (“N”) were shown. MTCH2 mRNA (D) and protein (in both mitochondrial fraction lysates and mitochondria-null lysates, E) expression levels in primary prostate cancer cells derived from four CRPC patients (“pPC-1”, “pPC-2”, “pPC-3”, and “pPC-4”) and primary human prostate epithelial cells (“pEpi1”) were shown. The data are expressed as mean ± standard deviation (SD). Statistical significance is marked by *P < 0.05 when compared to “pEpi1” cells or “N” tissue.

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