Fig. 1: ONECUT3 is a key transcription factor related to glycolysis in CRC. | Cell Death & Disease

Fig. 1: ONECUT3 is a key transcription factor related to glycolysis in CRC.

From: Transcription factor ONECUT3 regulates HDAC6/HIF-1α activity to promote the Warburg effect and tumor growth in colorectal cancer

Fig. 1

A Based on the known glycolysis-related gene clusters, TCGA-COAD samples were hierarchically clustered into high-glycolysis and low-glycolysis groups. B Screening for differentially expressed genes in the two groups. C The 127 upregulated genes were intersected with MsigDB: TF to obtain 11 transcription factors. D Ranking of log2|FC| values of 11 transcription factors. E Representative IHC images showed the level of ONECUT3 expression in CRC tissues and paracancerous tissues (scale bar: 50 μm).

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