Fig. 1: Both the mRNA and Protein level of PLOD3 were upregulated in CRC. | Cell Death & Disease

Fig. 1: Both the mRNA and Protein level of PLOD3 were upregulated in CRC.

From: Hypomethylation induced overexpression of PLOD3 facilitates colorectal cancer progression through TM9SF4-mediated autophagy

Fig. 1

A The mRNA level of PLOD3 was evaluated by qRT‒PCR in 80 CRC tissues and matched adjacent tissues. B The protein level of PLOD3 was measured by IHC in the TMA containing 80 CRC patients’ samples. C The protein level of PLOD3 were detected by WB in 8 fresh matched CRC tumor and adjacent tissues. D, E The mRNA and protein levels of PLOD3 were determined in CRC cell lines and NCM460 cells by qRT‒PCR and WB. F. PLOD3 overexpressed indicated a poor prognosis of CRC patient by K-Mcurve survival analysis. Data are presented as the mean ± SD at least three independent experiments, *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001 and P > 0.05, not significant (n.s.).

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