Fig. 3: PLOD3 promotes CRC cell proliferation, migration and invasion in vitro. | Cell Death & Disease

Fig. 3: PLOD3 promotes CRC cell proliferation, migration and invasion in vitro.

From: Hypomethylation induced overexpression of PLOD3 facilitates colorectal cancer progression through TM9SF4-mediated autophagy

Fig. 3

A, D CCK-8 assays were performed to evaluate the viability of PLOD3 knockdown or overexpression cells. B, C Colony formation assays were applied to detect the proliferation of CRC cells. E, F Flow cytometry was conducted to determine the apoptotic rates (LR + UR) of cells. G, H Transwell and wound healing assays were used to assess the abilities migration and invasion of CRC cells. LR, early apoptotic cells; UR, terminal apoptotic cells. Data are shown as the mean ± SD of three independent experiments, *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001and P > 0.05, not significant (n.s.).

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