Fig. 4: NAT10 promotes tumour growth and metastasis in vivo. | Cell Death & Disease

Fig. 4: NAT10 promotes tumour growth and metastasis in vivo.

From: NAT10 promotes the progression of clear cell renal cell carcinoma by regulating ac4C acetylation of NFE2L3 and activating AKT/GSK3β signaling pathway

Fig. 4

a The effect of NAT10 knockdown detected by qRT-PCR in A498 cells. b The protein level of NAT10 knockdown detected by western blot. c Representative images of subcutaneous tumours formed by the indicated cells. d The tumour volume of nude mice was monitored every 6 days. e Quantitative analysis of subcutaneous tumour after 66 days. f Left: Representative image of metastatic lung tumour. Right: quantitative analysis of fluorescence intensity of lung metastasis. g Left: Representative image of metastatic liver tumour. Right: quantitative analysis of fluorescence intensity of liver metastasis. h HE staining results of metastatic lung tumours (above) and metastatic liver tumours (below).

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