Fig. 2: The impact of UHRF1 on the biological phenotype of B-ALL cell lines.

A The knockout and restoration efficiency of UHRF1 in Nalm6 and Reh cell lines was assessed via Western blot analysis. B The cell proliferation was detected using MTS methods. C and D The apoptosis and cell cycle of leukemia cells was detected using the flow cytometry. N6: Nalm6.