Fig. 6: Evaluation of mitochondrial fuel oxidation in controls and TDP-43G376D mutant fibroblasts. | Cell Death & Disease

Fig. 6: Evaluation of mitochondrial fuel oxidation in controls and TDP-43G376D mutant fibroblasts.

From: Mitochondrial and energy metabolism dysfunctions are hallmarks of TDP-43G376D fibroblasts from members of an Amyotrophic Lateral Sclerosis family

Fig. 6

Pie charts indicate the relative dependency of cells on glucose, long-chain fatty acids and glutamine. Charts represent the results of three independent experiments. Following one-way ANOVA test with Tukey’s correction only fatty acids dependency showed a p-value of 0.0049 for Familial CTRL, 0.0024 for Asymptomatic fibroblasts, 0.0026 for early-stage fibroblasts and <0.0001 for the late-stage fibroblasts compared to unrelated CTRLs.

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