Table 2 Correlation between RIPK2 protein expression level and clinical characteristics of CRC.

From: RIPK2 promotes colorectal cancer metastasis by protecting YAP degradation from ITCH-mediated ubiquitination

Characteristics

RIPK2 protein expression level

P value

─ ~ + (N = 40)

++ ~ +++ (N = 112)

Age

61.725 ± 10.276

63.670 ± 10.056

0.305

Gender

  

0.798

 Male

23

67

 

 Female

17

45

 

T stage

  

0.663

 T1 & T2

3

11

 

 T3 & T4

37

101

 

N stage

  

0.021*

 N0

24

40

 

 N1

10

53

 

 N2

6

19

 

TNM stage

  

0.027*

 I

3

6

 

 II

21

34

 

 III

16

72

 

Recurrence

  

0.004*

 NO

33

64

 

 YES

7

48

 

Vascular invasion

  

0.131

 NO

39

98

 

 YES

1

14

 

Perineural invasion

  

0.095

 NO

33

77

 

 YES

7

35

 

Histological differentiation

  

0.536

 Well differentiated

2

10

 

 Moderately differentiated

25

74

 

 Poorly differentiated

13

28

 

 Tumor diameter/cm

5.225 ± 2.408

4.473 ± 1.837

0.078

Tumor site

  

0.858

 Right-side

16

49

 

 Left-side

15

42

 

 Rectum

9

21