Fig. 3: MTCH2 inhibits apoptosis in melanoma. | Cell Death & Disease

Fig. 3: MTCH2 inhibits apoptosis in melanoma.

From: MTCH2 regulates NRF2-mediated RRM1 expression to promote melanoma proliferation and dacarbazine insensitivity

Fig. 3

A, B Anti-apoptotic ability of MTCH2 knockdown or MTCH2 overexpressing A375, SK-MEL-21 and the control cells were evaluated by flow cytometry. C, D The expressions of apoptosis related factors Bcl2, Bax and Cl-Caspase3 in MTCH2 knockdown or MTCH2 overexpressing A375 and SK-MEL-21. The data represent three independent experiments. Each bar represents mean ± SD. p values were calculated using a Student’s t test (*p < 0.05, **p < 0.01, ***p < 0.001 vs. each control).

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