Fig. 3: SLC25A42 promotes in vivo GC tumor growth. | Cell Death & Disease

Fig. 3: SLC25A42 promotes in vivo GC tumor growth.

From: SLC25A42 promotes gastric cancer growth by conferring ferroptosis resistance through enhancing CPT2-mediated fatty acid oxidation

Fig. 3

A Subcutaneous tumor models were established using SLC25A42 silencing MKN-1 cells or overexpressing SNU-638 cells and their corresponding control cells (n = 6; Scale bar, 1 cm). The images of excised subcutaneous tumors were shown. B The weights of the tumors were compared in indicated groups. The expression levels of SLC25A42 (C) and Ki-67 (D) in the tissues from subcutaneous nude mice models were assessed by IHC assay. Scale bar, 20 μm. E The occurrence of apoptosis-positive cells in the tissues from subcutaneous nude mice models was assessed by TUNEL assay. Scale bar, 20 μm. F The number of nodules in the lungs from indicated groups was compared by the H&E analysis. Scale bar, 10 μm. *P < 0.05; ns, not significant.

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