Table 1 Characteristics of patients from whom liver samples were obtained.

From: Neurotensin promotes hepatic steatosis by regulating lipid uptake and mitochondrial adaptation in hepatocytes

Sample

Sex

Age (Years)

BMI

Diabetes

Diagnosisa

Clinical feature

PT#1

M

61

28.02

U

Normal

 

PT#2

M

38

29.24

N

Normal

 

PT#3

M

53

50.58

N

Normal

 

PT#4

F

18

30.83

N

Normal

 

PT#5

F

55

30.66

N

Normal

 

PT#6

M

52

42.37

Y

MASLD

30% steatosis, no fibrosis, no cirrhosis, no necrosis

PT#7

M

56

27.15

N

MASLD

50% steatosis (macrovesicular), no fibrosis, no cirrhosis, no necrosis

PT#8

M

58

35.98

N

MASLD

Severe steatosis

PT#9

M

20

29.55

N

MASLD

Severe steatosis

PT#10

M

44

35.67

Y

MASLD

20% steatosis (macrovesicular) + Stage 1 fibrosis

PT#11

M

20

35

N

MASH

80–90% steatosis (macrovesicular)+moderate periportal inflammation and focal active changes; necrosis present, no cirrhosis

PT#12

M

42

30.6

N

MASH

Steatohepatitis with >30% steatosis

PT#13

M

65

43.81

N

MASH

Steatohepatitis with 30% macrovesicular steatosis; mild portal inflammation

PT#14

M

36

34.03

N

MASH

Steatohepatitis with 30% macrovesicular steatosis+10% microvesicular steatosis; fibrosis (portal and bridging areas Stage 2–3)

PT#15

M

46

23.4

N

MASH

Steatohepatitis with 70% steatosis, ballooned hepatocytes, Mallory hyaline and lobular inflammation

  1. M male, F female, U unknown, Y yes, N no.
  2. aNormal, MASLD, MASH (N = 5 each).