Fig. 6: TRPM7 kinase domain deletion prevents pancreatic tumor development in vivo. | Cell Death & Disease

Fig. 6: TRPM7 kinase domain deletion prevents pancreatic tumor development in vivo.

From: The kinase domain of TRPM7 interacts with PAK1 and regulates pancreatic cancer cell epithelial-to-mesenchymal transition

Fig. 6

A Monitoring of tumor volume on SCID mice injected with PANC-1 Control (n = 6) and ΔK (n = 6, p < 0.001, Two-way ANOVA) for 60 days. B Masses in grams of tumors weighted after mice sacrifice (n = 6, p < 0.001, Student t-test). C Detection of micrometastasis in the liver and lungs of mice injected with PANC-1 Control and ΔK cells (Fisher test). Human GAPDH was used to detect micrometastasis in those organs. Results are shown as mean ± SD. ***p < 0.001.

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