Fig. 4: CSF1 exhibits high expression and decreased m6A modification levels in hybrids. | Cell Death & Disease

Fig. 4: CSF1 exhibits high expression and decreased m6A modification levels in hybrids.

From: Fusion of glioma-associated mesenchymal stem/stromal cells with glioma cells promotes macrophage recruitment and M2 polarization via m6A modification of CSF1

Fig. 4

A Volcano plot showing the distribution of differences in m6A modification levels between U87MG and Hybrid86. B Heatmap displaying the top 10 genes upregulation or downregulation in expression among those with decreased m6A levels in Hybrid86 compared to U87MG. C Western blotting analysis of CSF1 protein expression in GBM cells and hybrids. D Secreted CSF1 in the supernatants of GBM cells and hybrids were detected by ELISA. Examination of the effect of FTO knockdown on CSF1 expression in hybrids using qPCR (E), western blotting (F), and ELISA (G).

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