Fig. 8: Scheme of the effect of digoxin on the anoikis resistance of CCCs.
From: Digoxin promotes anoikis of circulating cancer cells by targeting Na+/K+-ATPase α3-isoform
Digoxin inhibits the translocation of α3NaK from cytoplasm to the PM upon cancer cell detachment, and promote anoikis in the CCCs, suppressing liver metastasis of gastric cancer.
