Fig. 7: KLF13 regulates EC cell proliferation, tumor growth, and lipid metabolism through GPIHBP1. | Cell Death & Disease

Fig. 7: KLF13 regulates EC cell proliferation, tumor growth, and lipid metabolism through GPIHBP1.

From: KLF13 promotes esophageal cancer progression and regulates triacylglyceride and free fatty acid metabolism through GPIHBP1

Fig. 7

A KLF13 and GPIHBP1 protein levels in KYSE450 cells transfected with shCtrl, shKLF13, and shKLF13 +GPIHBP, and KYSE30 cells transfected with Ctrl, KLF13, and KLF13+ shGPIHBP. B Cell viability of KYSE450 and KYSE30 cells. C, D Cell colony numbers of KYSE450 and KYSE30 cells. E–H TG and FFA concentrations in KYSE450 and KYSE30 cells. I Comparison of tumor sizes between the Ctrl, KLF13, and KLF13+shGPIHBP groups. J, K Comparison of tumor volumes and weights in the Ctrl, KLF13 and KLF13 + shGPIHBP groups (n = 5 mice per group). L KLF13, GPIHBP, and Ki67 expression in xenograft tumors evaluated by H&E staining. Scale bar = 100 µm. M, N TG and FFA concentrations in tumors from Ctrl, KLF13, and KLF13+shGPIHBP group mice.

Back to article page