Fig. 3: Impact of S100A11 on colorectal cancer tumour growth in vivo.
From: USP14/S100A11 axis promote colorectal cancer progression by inhibiting cell senescence
A Representative images from S100A11 knockdown groups and control. B Tumour weights from the knockdown study. C Tumour volume growth curves for S100A11 knockdown. D Representative images from S100A11 overexpression and control groups. E Tumour weights from the overexpression study. F Tumour volume growth curves for S100A11 overexpression. G Histological analysis of Ki-67, and S100A11 staining in knockdown tumours. H Histological analysis in overexpression tumours. I Histological sections and quantification of metastatic nodules in lung tissues after S100A11 knockdown. J Histological sections and quantification of metastatic nodules in lung tissues following S100A11 overexpression. Representative images demonstrate increased metastasis in the oe-S100A11 group compared to the vector control. **p < 0.01, ***p < 0.001.
