Fig. 2: Serum starvation and aging-mediated physiological stress elevate PDK4 level.
From: The impact of ERUPR on mitochondrial integrity mediated by PDK4
A SH-SY5Y cells were treated with high (10%) and low (0.1%) levels of FBS concentrations and immunoblotting of cell lysates were performed to detect PDK4 and BiP protein levels. B Graphs show the alterations in PDK4 and BiP proteins. Data represent the mean ± SEM of 4 independent experiments. C Immunoblotting of brain region-specific lysates (hippocampus, cortex, striatum, and cerebellum) of 1-month and 1-year-old rats was performed to check the expression of indicated proteins. D Graphs represent the altered protein level and represented as the mean ± SEM of 5 animals/group. *p ≤ 0.05; **p ≤ 0.01; ns not significant (estimated via unpaired two-tailed Student’s t-test).
